1,4-Dioxane

Q: Is 1,4-Dioxane harmful in cosmetics?

Yes, 1,4-Dioxane is considered harmful due to its potential carcinogenic effects and is present in trace amounts in some cosmetics. It is recommended to minimize exposure.

Q: How does 1,4-Dioxane form in consumer products?

1,4-Dioxane can form as a byproduct during the ethoxylation process, which is used to make ingredients like PEG compounds more soluble and milder.

Q: Can 1,4-Dioxane be absorbed through the skin?

Yes, 1,4-Dioxane can be absorbed through the skin, and prolonged exposure may contribute to systemic health risks.

Q: How can I avoid 1,4-Dioxane in products?

To avoid 1,4-Dioxane, opt for products labeled as '1,4-Dioxane free' and avoid those containing ingredients with 'eth' in the name, such as sodium laureth sulfate.

CAS: 123-91-1 | Synonyms: Diethylene dioxide, Glycol ethylene ether, Dioxan +2

Safer alternative: Cocamidopropyl Betaine

Toxicity Score

9 /10

Avoid

Primary Concern

carcinogenicity

Found In

Shampoos, Body Wash, Liquid Soaps

Persona Risk

High Risk for Wellness & Longevity

Put Simply

1,4-Dioxane is a sneaky byproduct that can show up in small amounts in things like shampoos, body washes, and laundry detergents. It's linked to cancer risk and can irritate your skin and eyes, so it's something to keep an eye on. Try to choose products that say they're free from this ingredient to play it safe.

Clinical Summary

1,4-Dioxane is a chemical byproduct that can be found in trace amounts in cosmetic products which utilize ethoxylating processes. It is classified as 'possibly carcinogenic to humans' by the International Agency for Research on Cancer (IARC) and has demonstrated organ toxicity in animal studies. Exposure to high levels can cause skin and eye irritation, with regulations and guidelines suggesting minimization of its presence in consumer products.

Identified Health Risks

carcinogenicity

organ toxicity

skin and eye irritation

What This Score Means

Avoid. This ingredient scores 9/10 on our toxicity scale. Strong clinical evidence links it to serious health concerns. We recommend swapping any product containing this ingredient.

Regulatory Status

Cross-referenced safety assessments from regulatory bodies

Organization

Rating

Concern

IARC

Group 2B

Possible human carcinogen

NIOSH

Carcinogen

Inhalation and dermal exposure risk

Also Listed On Labels As

Diethylene dioxide Glycol ethylene ether Dioxan p-Dioxane Dianhydrodiethylene glycol

Risk by Health Profile

Wellness & Longevity High Risk

Long-term exposure is linked to potential carcinogenic effects.

Skin & Allergy High Risk

Exposure can cause skin irritation upon contact, especially at higher concentrations.

Frequently Asked Questions

Is 1,4-Dioxane harmful in cosmetics?

How does 1,4-Dioxane form in consumer products?

Can 1,4-Dioxane be absorbed through the skin?

How can I avoid 1,4-Dioxane in products?

Sources & Citations

[1]
EWG Skin Deep (14-Dioxane)
[2]
PubMed Central (PMID: 18531710)
[3]
ECHA

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